Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 9/20 | 0.74 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644860 | 0.87 | NR4A2 (0.56) | NR4A2MEN1KMT2AMITFLMNA | |
| SCHEMBL12480777 | 0.87 | NR4A2 (0.56) | NR4A2MEN1KMT2AMITFLMNA | |
| SCHEMBL31375050 | 0.87 | NR4A2 (0.55) | NR4A2MEN1KMT2AMITFLMNA | |
| SCHEMBL5068806 | 0.85 | NR4A2 (1.00) | NR4A2CREBBPMEN1KMT2AMITF | |
| SCHEMBL28182662 | 0.84 | LMNA (0.56) | NR4A2MEN1KMT2AMITFLMNA | |
| SCHEMBL24855192 | 0.82 | NR4A2 (0.50) | NR4A2MEN1KMT2AMITFLMNA | |
| SCHEMBL30844608 | 0.82 | NR4A2 (0.50) | NR4A2MEN1KMT2AMITFLMNA | |
| SCHEMBL24855193 | 0.82 | NR4A2 (0.50) | NR4A2MEN1KMT2AMITFLMNA | |
| SCHEMBL1466529 | 0.82 | NR4A2 (0.65) | NR4A2CREBBPMEN1KMT2AMITF | |
| SCHEMBL29989077 | 0.82 | NR4A2 (0.50) | NR4A2MEN1KMT2AMITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |