Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.70 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.70 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.70 |
| ▸ | SPOP | O43791 | 12/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332149 | 1.00 | TDP1 (0.70) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL11586381 | 0.82 | TDP1 (1.00) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL11586385 | 0.82 | TDP1 (1.00) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL9481956 | 0.82 | TDP1 (1.00) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL16716450 | 0.82 | TDP1 (1.00) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL9743135 | 0.82 | TDP1 (1.00) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL17135384 | 0.82 | TDP1 (1.00) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL13806385 | 0.81 | TDP1 (0.65) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL11585026 | 0.80 | ALDH1A1 (0.73) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL11587206 | 0.80 | MAPT (0.67) | TDP1MAPTPOLBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008673-A2 | CRYSTALLINE ANHYDROUS CEFDINIR AND CRYSTALLINE CEFDINIR HYDRATES | ABBOTT LABORATORIES (US) | 2007-01-18 | — | — | WO | disclosed |