Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 5/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903204 | 0.84 | KDM4E (0.43) | EGLN1MAPTNPSR1GRM5 | |
| SCHEMBL4904831 | 0.82 | ALDH1A1 (0.39) | EGLN1USP2MAPTALOX15TSHR | |
| Hydrochloric Acid SCHEMBL4904519 | 0.81 | ALDH1A1 (0.38) | EGLN1USP2MAPTALOX15TSHR | |
| SCHEMBL4896598 | 0.79 | ALDH1A1 (0.43) | MAPTNPSR1JAK2JAK1TYK2 | |
| SCHEMBL4895051 | 0.78 | ALDH1A1 (0.45) | EGLN1MAPTNPSR1WNT3AABL1 | |
| Hydrochloric Acid SCHEMBL4896673 | 0.77 | ALDH1A1 (0.45) | EGLN1MAPTNPSR1WNT3AABL1 | |
| SCHEMBL4899608 | 0.77 | CYP1A2 (0.41) | USP2MAPTALOX15TSHRSMN1; SMN2 | |
| SCHEMBL4899881 | 0.77 | TSHR (0.39) | MAPTALOX15TSHRNPSR1GRM5 | |
| SCHEMBL4892363 | 0.75 | CYP1A2 (0.35) | EGLN1MAPTNPSR1CDK2 | |
| SCHEMBL3128924 | 0.72 | KDM4E (0.42) | EGLN1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737852-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100349-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2005-10-27 | — | — | WO | disclosed |