Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332472 | 1.00 | KMT2A (0.42) | KMT2AMEN1PPARGP2RX3PLA2G4B | |
| SCHEMBL5311776 | 0.94 | KMT2A (0.46) | KMT2AMEN1PLA2G4BFABP1NPC1 | |
| SCHEMBL5311769 | 0.94 | KMT2A (0.46) | KMT2AMEN1PLA2G4BFABP1NPC1 | |
| SCHEMBL14530949 | 0.82 | PLA2G4B (0.48) | KMT2APPARGP2RX3PLA2G4BNR4A2 | |
| SCHEMBL5312906 | 0.81 | KMT2A (0.59) | KMT2APPARGPLA2G4BFABP1NPC1 | |
| SCHEMBL5312903 | 0.81 | KMT2A (0.59) | KMT2APPARGPLA2G4BFABP1NPC1 | |
| SCHEMBL14530963 | 0.81 | KMT2A (0.47) | KMT2AMEN1PPARGPLA2G4BFABP1 | |
| SCHEMBL5310865 | 0.78 | KMT2A (0.57) | KMT2APPARGPLA2G4BFABP1NPC1 | |
| SCHEMBL5310869 | 0.78 | KMT2A (0.57) | KMT2APPARGPLA2G4BFABP1NPC1 | |
| SCHEMBL5313656 | 0.78 | KMT2A (0.44) | KMT2APPARGPLA2G4BFABP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |