Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425727 | 0.94 | PTGDR2 (0.56) | HTR6PTGDR2PTGDR | |
| SCHEMBL5332897 | 0.94 | HTR6 (0.51) | HTR6PTGDR2PTGDR | |
| SCHEMBL5331999 | 0.92 | HTR6 (0.51) | HTR6PTGDR2PTGDR | |
| SCHEMBL5331610 | 0.91 | HTR6 (0.52) | HTR6PTGDR2PTGDR | |
| SCHEMBL5327797 | 0.90 | HTR6 (0.49) | HTR6PTGDR2PTGDRCYP3A4CYP2D6 | |
| SCHEMBL5407866 | 0.90 | PTGDR2 (0.52) | HTR6PTGDR2PTGDR | |
| SCHEMBL5327986 | 0.87 | HTR6 (0.52) | HTR6PTGDR2PTGDR | |
| SCHEMBL5420513 | 0.87 | PTGDR2 (0.44) | HTR6PTGDR2PTGDRCYP3A4CYP2D6 | |
| SCHEMBL5330691 | 0.86 | HTR6 (0.46) | HTR6PTGDR2PTGDR | |
| SCHEMBL5328962 | 0.85 | PTGDR2 (0.53) | HTR6PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |