Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315121 | 0.82 | GAA (0.48) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL5317125 | 0.80 | MAPK1 (0.45) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL5332098 | 0.76 | MEN1 (0.49) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL5315815 | 0.76 | KDM4E (1.00) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL6330357 | 0.75 | KDR (0.65) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL5337352 | 0.73 | GAA (0.43) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL5316078 | 0.71 | KDM4E (0.70) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL4802259 | 0.71 | MAPK1 (0.56) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL5554204 | 0.70 | MAP3K8 (0.71) | PIM1MAP3K8MAP2K1 | |
| SCHEMBL3796867 | 0.68 | KDM4E (1.00) | MAPTKMT2AMEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | disclosed |