Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | YES1 | P07947 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333560 | 0.90 | MEN1 (0.55) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL5337352 | 0.88 | GAA (0.43) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL5339343 | 0.87 | ICAM1 (0.42) | MEN1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL5330795 | 0.86 | IRAK4 (0.47) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL5313426 | 0.83 | PTGS1 (0.46) | MEN1KMT2AGAAMAPTUSP2 | |
| SCHEMBL5331010 | 0.82 | CSNK2A1 (0.51) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL5317673 | 0.81 | TSHR (0.42) | GAAMAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL5315121 | 0.81 | GAA (0.48) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL5329633 | 0.81 | KMT2A (0.52) | MEN1KMT2AEGFR | |
| SCHEMBL5335650 | 0.80 | EPAS1 (0.43) | MEN1KMT2AMAPTKDRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | disclosed |