SCHEMBL5333147

SCHEMBL5333147

CCC(NC(N)=O)(NC(N)=O)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.31
TSHR P16473 2/20 0.30
NFKB1 P19838 2/20 0.30
CYP1A2 P05177 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11124997 0.81
SCHEMBL11406496 0.74 LMNA (0.33) CRBNTSHRNFKB1CYP1A2MAOA
SCHEMBL9115954 0.72
SCHEMBL729760 0.72
SCHEMBL8719013 0.72 CRBN (0.32) CRBNTSHRNFKB1CYP1A2MAOA
SCHEMBL11410132 0.72 CRBN (0.32) CRBNTSHRNFKB1CYP1A2MAOA
SCHEMBL3267124 0.70
SCHEMBL10572775 0.70
Fluoride SCHEMBL28884982 0.70 EPHX1 (0.42) CRBN
Ammonia Solution, Strong SCHEMBL27986024 0.70 EPHX1 (0.42) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007034064-A1 CONTINUOUS SYNTHESIS OF AN $G(A)-AMINO ACID FROM A CYANHYDRIN OF $G(A)-AMINO ACID WITHOUT THE ISOLATION OF INTERMEDIATE PRODUCTS ADISSEO FRANCE S.A.S. (FR) 2007-03-29 WO disclosed
WO-2007034066-A1 CONTINUOUS SYNTHESIS OF METHIONINE FROM 2-HYDROXY-4-(METHYLTHIO)BUTYRONITRILE, CO2, NH3 AND H2O WITHOUT THE ISOLATION OF INTERMEDIATE PRODUCTS ADISSEO FRANCE S.A.S. (FR) 2007-03-29 WO disclosed