Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.36 |
| ▸ | NPR3 | P17342 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130851 | 0.92 | NPR3 (0.36) | ITGB1ITGA4NPR3 | |
| SCHEMBL5263353 | 0.88 | ITGB1 (0.36) | ITGB1ITGA4NPR3 | |
| SCHEMBL5264342 | 0.88 | ITGB1 (0.36) | ITGB1ITGA4NPR3 | |
| SCHEMBL6537276 | 0.86 | NPR3 (0.37) | ITGB1ITGA4NPR3 | |
| SCHEMBL5333186 | 0.85 | PIM1 (0.34) | ITGB1ITGA4TRPV1 | |
| SCHEMBL5149509 | 0.82 | TRPV1 (0.39) | ITGB1ITGA4NPR3TRPV1 | |
| SCHEMBL5259088 | 0.81 | ITGB1 (0.41) | ITGB1ITGA4 | |
| SCHEMBL2982616 | 0.79 | ITGB1 (0.51) | ITGB1ITGA4NPR3 | |
| SCHEMBL7098869 | 0.77 | ITGB1 (0.57) | ITGB1ITGA4 | |
| SCHEMBL5259895 | 0.77 | ITGB1 (0.35) | ITGB1ITGA4NPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332132-B1 | ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES | UCB PHARMA SA (BE) | 2007-10-10 | — | — | EP | disclosed |