Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Alcohol SCHEMBL1500423 | 0.96 | TSHR (0.67) | TSHRTRPA1TDP1LTA4HLMNA | |
| Benzyl Alcohol SCHEMBL1170669 | 0.91 | TSHR (0.61) | TSHRTRPA1TDP1LTA4HLMNA | |
| Benzyl Alcohol SCHEMBL27674445 | 0.88 | TSHR (0.47) | TSHRTRPA1TDP1MAPK1 | |
| Benzyl Alcohol SCHEMBL4915528 | 0.86 | TSHR (0.74) | TSHRTRPA1TDP1LTA4HSLC6A2 | |
| Benzyl Alcohol SCHEMBL29091766 | 0.85 | TSHR (0.58) | TSHRTRPA1TDP1LTA4HLMNA | |
| Benzyl Alcohol SCHEMBL9293892 | 0.84 | TSHR (0.52) | TSHRTRPA1SLC6A2TAAR1MAOA | |
| Benzyl Alcohol SCHEMBL3949110 | 0.84 | TSHR (0.70) | TSHRTRPA1TDP1LTA4HSLC6A2 | |
| Benzyl Alcohol SCHEMBL4884105 | 0.83 | TSHR (0.88) | TSHRTRPA1TDP1LTA4HLMNA | |
| Phenylethyl Alcohol SCHEMBL27856433 | 0.83 | TDP1 (0.70) | TSHRTRPA1TDP1 | |
| Benzyl Alcohol SCHEMBL9753185 | 0.80 | TSHR (0.47) | TSHRTRPA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038496-A2 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF HYDROXY CARBOXYLIC ACIDS, THE USE OF THE SAME AS PERCUTANEOUS PERMEATION ENHANCERS | CHEMIC LABORATORIES, INC. (US) | 2007-04-05 | — | — | WO | disclosed |