Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Alcohol SCHEMBL1500423 | 0.84 | TSHR (0.67) | TSHRTRPA1CES2CES1 | |
| Benzyl Alcohol SCHEMBL28238651 | 0.82 | TSHR (0.64) | TSHRLAP3ANPEPCES2CES1 | |
| Benzyl Alcohol SCHEMBL5333203 | 0.80 | TSHR (0.61) | TSHRTRPA1CES2CES1 | |
| Benzyl Alcohol SCHEMBL1170669 | 0.80 | TSHR (0.61) | TSHRTRPA1 | |
| Benzyl Alcohol SCHEMBL9293892 | 0.77 | TSHR (0.52) | TSHRTRPA1CES2CES1 | |
| Benzyl Alcohol SCHEMBL4915528 | 0.75 | TSHR (0.74) | TSHRTRPA1CYP2D6 | |
| Benzyl Alcohol SCHEMBL2314664 | 0.75 | TSHR (0.74) | TSHRLAP3ANPEPCES2CES1 | |
| Propylene Glycol SCHEMBL4585432 | 0.75 | TDP1 (0.59) | TSHR | |
| Benzyl Alcohol SCHEMBL25192635 | 0.75 | TSHR (0.54) | TSHRMEN1KMT2ATRPA1HDAC3 | |
| Benzyl Alcohol SCHEMBL3949110 | 0.73 | TSHR (0.70) | TSHRMEN1KMT2ATRPA1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008733-A1 | STABLE CREAM AND LOTION BASES FOR LIPOPHILIC DRUG COMPOSITIONS | SCHERING CORPORATION (US) | 1991-06-27 | — | — | WO | disclosed |