SCHEMBL5333332

SCHEMBL5333332

CN(CCC[As](C)CCC(=O)O)CC(=O)Nc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314374 0.87 LTA4H (0.93) LTA4H
SCHEMBL5313760 0.84 LTA4H (0.86) LTA4H
SCHEMBL5660215 0.83 LTA4H (0.82) LTA4H
SCHEMBL5660267 0.82 LTA4H (0.95) LTA4H
SCHEMBL5664362 0.82 LTA4H (1.00) LTA4H
SCHEMBL5661877 0.81 LTA4H (0.93) LTA4H
SCHEMBL5661515 0.81 LTA4H (0.80) LTA4H
SCHEMBL5659446 0.80 LTA4H (0.78) LTA4H
SCHEMBL5313170 0.79 LTA4H (0.79) LTA4H
SCHEMBL5661889 0.79 LTA4H (0.85) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007079003-A2 AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-07-12 WO disclosed