Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317388 | 0.93 | CNR1 (0.51) | CNR1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5340360 | 0.82 | AKT1 (0.46) | MAPTTSPOPOLBGMNNLMNA | |
| SCHEMBL5341242 | 0.81 | AKT1 (0.42) | CNR1MAPTTSPOPOLBGMNN | |
| Hydrochloric Acid SCHEMBL5348937 | 0.81 | CNR1 (0.56) | CNR1AKT1AKT2PTGS2SLC2A1 | |
| SCHEMBL5340752 | 0.80 | CNR1 (0.53) | CNR1TSPOAKT1AKT2SLC2A1 | |
| SCHEMBL5337475 | 0.78 | CNR1 (0.50) | CNR1ALDH1A1MAPTLMNA | |
| SCHEMBL5335061 | 0.77 | AKT1 (0.42) | MAPTTSPOPOLBGMNNLMNA | |
| SCHEMBL5341397 | 0.77 | AKT1 (0.45) | MAPTTSPOPOLBGMNNLMNA | |
| SCHEMBL5335616 | 0.77 | AKT1 (0.45) | MAPTTSPOPOLBGMNNLMNA | |
| SCHEMBL5344434 | 0.76 | TSPO (0.45) | MEN1ALDH1A1MAPTKMT2ATSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |