SCHEMBL533393

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2639364	0.79	KMT2A (0.45)	MEN1KMT2ANPC1RAB9AATM
	SCHEMBL28305796	0.79	NPC1 (0.47)	MEN1KMT2ANPC1RAB9AATM
	SCHEMBL534270	0.76	MEN1 (0.40)	MEN1KMT2ANPC1RAB9AATM
	SCHEMBL533483	0.76	MEN1 (0.40)	MEN1KMT2ANPC1RAB9AATM
	SCHEMBL533189	0.76	HDAC4 (0.47)	TRPV3
	SCHEMBL533167	0.73	CLK4 (0.46)	NPC1RAB9ACYP1A2CYP3A4LMNA
	SCHEMBL534163	0.72	ROCK1 (0.33)	MEN1KMT2ANPC1RAB9AATM
	SCHEMBL533615	0.72	NPC1 (0.41)	MEN1KMT2ANPC1MAPTCYP1A2
	SCHEMBL533236	0.72	TRPV3 (0.39)	MEN1KMT2ACYP1A2POLBTRPV3
	SCHEMBL28507447	0.72	KDM4E (0.36)	MEN1KMT2ANPC1RAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.