Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498284 | 0.90 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL2129032 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL2127861 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL3500247 | 0.80 | NPC1 (0.56) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL5338834 | 0.80 | NPC1 (0.56) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| Bromide SCHEMBL1691775 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL1691270 | 0.78 | NR4A2 (0.71) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL5337094 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL5337257 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL2127590 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |