Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281940 | 0.89 | MAPT (0.62) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL4919617 | 0.84 | MEN1 (0.65) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL12830307 | 0.82 | MAPT (0.55) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL4920382 | 0.82 | MAPT (0.65) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19566127 | 0.81 | KDM4E (0.60) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL5713545 | 0.80 | MAPT (0.67) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL14807633 | 0.80 | DUSP3 (0.82) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL2754063 | 0.80 | MEN1 (0.60) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL12021634 | 0.79 | MAPT (0.58) | KDM4EL3MBTL1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL2686124 | 0.78 | KDM4E (0.75) | KDM4EL3MBTL1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |