Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676716 | 0.70 | POLB (0.39) | POLB | |
| SCHEMBL1194880 | 0.66 | GSK3A (0.47) | POLB | |
| SCHEMBL18843394 | 0.64 | HTT (0.36) | POLB | |
| SCHEMBL18840159 | 0.64 | HTT (0.36) | POLB | |
| SCHEMBL1537360 | 0.64 | HTT (0.39) | POLB | |
| SCHEMBL18840191 | 0.63 | CHRM2 (0.34) | — | |
| SCHEMBL18840173 | 0.63 | CHRM2 (0.31) | — | |
| SCHEMBL3678842 | 0.63 | MAPT (0.33) | POLB | |
| SCHEMBL18840176 | 0.62 | POLB (0.30) | POLB | |
| SCHEMBL18840165 | 0.62 | POLB (0.30) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074390-A2 | PROCESS FOR PREPARING RHODANINE-3-ACETIC ACID: A KEY INTERMEDIATED OF EPALRESTAT | KHAMAR BAKULESH MAFATLAL (IN) | 2007-07-05 | — | — | WO | disclosed |