Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 18/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617204 | 1.00 | CHRM3 (0.51) | CHRM3CHRM2CHRM1CHRM4NPC1 | |
| SCHEMBL3614676 | 0.85 | CHRM3 (0.48) | CHRM3CHRM2CHRM1CHRM4NPC1 | |
| SCHEMBL15329372 | 0.82 | CHRM3 (0.55) | CHRM3CHRM2CHRM1CHRM4NPC1 | |
| SCHEMBL3616029 | 0.80 | CHRM3 (0.45) | CHRM3CHRM2CHRM1CHRM4NPC1 | |
| SCHEMBL3622658 | 0.80 | CHRM3 (0.70) | CHRM3CHRM2CHRM1 | |
| SCHEMBL15127538 | 0.79 | CHRM3 (0.52) | CHRM3CHRM2CHRM1CHRM4NPC1 | |
| SCHEMBL3621284 | 0.77 | CHRM3 (0.49) | CHRM3CHRM2CHRM1NPC1MAPT | |
| SCHEMBL3634718 | 0.76 | CHRM3 (0.49) | CHRM3CHRM2CHRM1CHRM4NPC1 | |
| SCHEMBL4636347 | 0.76 | CHRM3 (0.55) | CHRM3CHRM2CHRM1CHRM4NPC1 | |
| SCHEMBL156567 | 0.76 | KEAP1 (0.58) | CHRM3CHRM2CHRM1CHRM4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828174-A1 | AZABICYCLIC MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006054162-A1 | AZABICYCLIC MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-05-26 | — | — | WO | disclosed |