Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534227 | 0.92 | PTGER2 (0.41) | PTGER2ITGB3ITGA2BITGAVSLC1A3 | |
| SCHEMBL533374 | 0.92 | USP2 (0.35) | PTGER2ITGB3ITGA2BITGAVSLC1A3 | |
| SCHEMBL534362 | 0.88 | PTGER2 (0.36) | PTGER2ITGB3ITGA2BITGAVSLC1A3 | |
| SCHEMBL534170 | 0.85 | PTGER2 (0.40) | PTGER2ITGB3ITGAVSLC1A3SLC1A2 | |
| SCHEMBL533439 | 0.84 | PTGER2 (0.34) | PTGER2LMNATP53MAPTTRPM8 | |
| SCHEMBL533440 | 0.82 | PTGER2 (0.52) | PTGER2 | |
| SCHEMBL534320 | 0.81 | PTGER2 (0.38) | PTGER2ITGB3ITGAVSLC1A3SLC1A2 | |
| SCHEMBL533795 | 0.81 | SLC1A3 (0.35) | PTGER2ITGAVSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL534592 | 0.81 | PTGER2 (0.44) | PTGER2ITGAVSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10322183 | 0.81 | PTPRB (0.35) | PTGER2ITGB3ITGAVSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648097-B2 | Pyridylaminoacetic acid compound | UBE INDUSTRIES, LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20120190852-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF GLAUCOMA | UBE INDUSTRIES, LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190852-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF GLAUCOMA | F12, C1S, AKR1C3 | PTGER2 24/4885ITGB3 3236/4885ITGA2B 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.