Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 6/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | USP8 | P40818 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533441 | 0.92 | PTGER2 (0.34) | PTGER2ITGB3ITGA2BSLC1A3SLC1A2 | |
| SCHEMBL533374 | 0.91 | USP2 (0.35) | PTGER2ITGB3ITGA2BMMP13SLC1A3 | |
| SCHEMBL533551 | 0.88 | PTGER2 (0.44) | PTGER2ITGB3ITGA2BMMP13SLC1A3 | |
| SCHEMBL534592 | 0.86 | PTGER2 (0.44) | PTGER2MMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL534320 | 0.85 | PTGER2 (0.38) | PTGER2ITGB3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10323317 | 0.84 | SLC1A3 (0.34) | PTGER2SLC1A3SLC1A2SLC1A1F2 | |
| SCHEMBL533795 | 0.84 | SLC1A3 (0.35) | PTGER2MMP13SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10322183 | 0.83 | PTPRB (0.35) | PTGER2ITGB3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL533428 | 0.82 | SLC1A3 (0.33) | PTGER2ITGB3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL533698 | 0.82 | PTGER2 (0.42) | PTGER2ITGB3MMP13SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648097-B2 | Pyridylaminoacetic acid compound | UBE INDUSTRIES, LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20120190852-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF GLAUCOMA | UBE INDUSTRIES, LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190852-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF GLAUCOMA | F12, C1S, AKR1C3 | PTGER2 24/4885ITGB3 3236/4885ITGA2B 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.