Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325123 | 0.83 | AR (0.64) | ARSHBGLMNAMAPTPGR | |
| SCHEMBL5327817 | 0.82 | AR (0.45) | ARSHBGLMNAMAPTPGR | |
| SCHEMBL14569123 | 0.82 | AR (0.45) | ARSHBGLMNAMAPTPGR | |
| SCHEMBL3453517 | 0.82 | AR (0.50) | ARSHBGLMNAMAPTPGR | |
| SCHEMBL3453564 | 0.81 | SHBG (0.52) | ARSHBGPGR | |
| SCHEMBL13125419 | 0.81 | SHBG (0.52) | ARSHBGPGR | |
| SCHEMBL3452256 | 0.76 | SHBG (0.46) | ARSHBGPGR | |
| SCHEMBL5329105 | 0.73 | SHBG (0.71) | ARSHBGPGR | |
| SCHEMBL6011908 | 0.73 | SHBG (0.71) | ARSHBGPGR | |
| SCHEMBL13125422 | 0.73 | SHBG (0.71) | ARSHBGPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196074-B2 | Methods of making, using and pharmaceutical formulations comprising 7α, 11β-dimethyl-17β-hydroxyestra-4, 14-dien-3-one and 17 esters thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-03-27 | — | — | US | claimed |
| EP-1379253-B1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA,11BETA-DIMETHYL-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | US GOV HEALTH & HUMAN SERV (US) | 2006-03-29 | — | — | EP | disclosed |