Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812900 | 0.92 | IDO1 (0.47) | IDO1TSHRHTTL3MBTL1HPGD | |
| SCHEMBL8090483 | 0.83 | IDO1 (0.49) | IDO1HTTL3MBTL1HPGDTAAR1 | |
| Hydroquinone SCHEMBL8078917 | 0.80 | IDO1 (0.45) | IDO1HTTL3MBTL1HPGDTAAR1 | |
| SCHEMBL5333860 | 0.78 | APLNR (0.51) | TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL11310785 | 0.78 | HTT (0.64) | IDO1HTTL3MBTL1HPGDTAAR1 | |
| SCHEMBL6825597 | 0.78 | TSHR (0.55) | TSHRHTTHPGDTAAR1ALDH1A1 | |
| Resorcinol SCHEMBL8090436 | 0.77 | TTR (0.43) | IDO1HTTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL10782273 | 0.76 | HTT (0.62) | IDO1HTTL3MBTL1HPGDTAAR1 | |
| SCHEMBL18398576 | 0.76 | IDO1 (0.56) | IDO1HTTL3MBTL1HPGDTAAR1 | |
| SCHEMBL31072414 | 0.76 | IDO1 (0.56) | IDO1HTTL3MBTL1HPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235666-B2 | Sulfonation of 3-(hydroxymethyl)-5,5-diphenylimidazolidine-2,4-dione followed by phosphating in the presence of trisubstituted aliphatic amine base and a polar aprotic solvent; anticonvulsants, antiepileptic and antiarrhythmia agent | CILAG LTD. (CH) | 2007-06-26 | — | — | US | claimed |
| US-9126451-B2 | Thermal recording materials | APPVION, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20150165806-A1 | THERMAL RECORDING MATERIALS | APPVION, INC. (US) | 2015-06-18 | — | — | US | disclosed |