Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334905 | 0.89 | TRPV4 (0.31) | TRPV4 | |
| SCHEMBL13826034 | 0.88 | TRPV4 (0.33) | TRPV4ATM | |
| SCHEMBL28966761 | 0.86 | TRPV4 (0.32) | TRPV4ATM | |
| SCHEMBL20521848 | 0.86 | TRPV4 (0.32) | TRPV4ATM | |
| SCHEMBL27516214 | 0.82 | TRPV4 (0.33) | TRPV4ATM | |
| SCHEMBL20596142 | 0.82 | TRPV4 (0.33) | TRPV4ATM | |
| SCHEMBL5333617 | 0.82 | TRPV4 (0.33) | TRPV4ATM | |
| SCHEMBL20596085 | 0.82 | TRPV4 (0.33) | TRPV4ATM | |
| SCHEMBL28966745 | 0.78 | TRPV4 (0.31) | TRPV4 | |
| SCHEMBL9625848 | 0.77 | TRPV4 (0.41) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030018204-A1 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-01-23 | — | — | US | claimed |
| US-7217827-B2 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-6916959-B2 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20050090691-A1 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD., A JAPAN CORPORATION | 2005-04-28 | — | — | US | disclosed |
| US-20030018204-A1 | Halogen-containing aromatic compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-1256564-A1 | Halogen-containing aromatic compound | Nippon Shokubai Co., Ltd. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090691-A1 | Halogen-containing aromatic compound | TYR, AFF4, DDT | TRPV4 99/4885ATM 2100/4885 |
| US-20030018204-A1 | Halogen-containing aromatic compound | TYR, AFF4, DDT | TRPV4 99/4885ATM 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.