Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335037 | 1.00 | EGLN1 (0.44) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL5141226 | 0.84 | EGLN1 (0.43) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL522422 | 0.81 | EGLN1 (0.45) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523053 | 0.80 | EGLN1 (0.43) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523849 | 0.79 | EGLN1 (0.43) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL521832 | 0.76 | EGLN1 (0.69) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL17739898 | 0.76 | EGLN1 (0.69) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL521831 | 0.76 | EGLN1 (0.69) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523239 | 0.76 | EGLN1 (0.50) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523063 | 0.74 | EGLN1 (0.70) | EGLN1FTOBBOX1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047194-A2 | METHODS FOR TREATING MITF-RELATED DISORDERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |