SCHEMBL5335063

SCHEMBL5335063

C=C[Si](C)(C)OC1CC2CCC1C2

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.37
PDGFRB P09619 2/20 0.32
PDGFRA P16234 2/20 0.32
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5335706 0.85 ATM (0.37) ATMPDGFRBPDGFRACYP19A1
SCHEMBL5341534 0.81 ATM (0.39) ATMPDGFRBPDGFRACYP19A1
SCHEMBL25442790 0.71
SCHEMBL5338121 0.71
SCHEMBL14501192 0.71
SCHEMBL5340916 0.70 MCHR1 (0.34)
SCHEMBL75104 0.70 ATM (0.42) ATMCYP19A1
SCHEMBL17485828 0.67
SCHEMBL7648170 0.67 ATM (0.37) ATM
SCHEMBL18912866 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220810-B2 Polymer film and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-7217830-B2 Organic silicon compound and method for preparing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-15 US disclosed
US-20060009600-A1 Polymer film and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-01-12 US disclosed
US-20060004219-A1 Organic silicon compound and method for preparing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004219-A1 Organic silicon compound and method for preparing the same AR, PKD1, SKP2 ATM 539/4885PDGFRB 769/4885PDGFRA 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.