Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303954 | 0.89 | PPARA (0.61) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL805971 | 0.89 | PPARA (0.61) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL1304683 | 0.85 | PPARA (0.61) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL1304254 | 0.84 | RAB9A (0.69) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL1305108 | 0.84 | PPARA (0.54) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL1304551 | 0.82 | EPHX2 (0.63) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL1305198 | 0.82 | PPARA (0.53) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL16743451 | 0.82 | PPARA (0.56) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL1304620 | 0.81 | CYP1A2 (0.60) | PPARAEPHX2MEN1KMT2ACYP1A2 | |
| SCHEMBL1305432 | 0.80 | MAPT (0.64) | PPARAEPHX2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044309-A2 | DEVICE AND METHOD FOR INHIBITING AGE COMPLEX FORMATION | VASIX CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-6337350-B1 | CROSSLINKING INHIBITION OF PROTEINS | CITY OF HOPE | 2002-01-08 | — | — | US | disclosed |