Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335661 | 0.94 | HTR1A (0.65) | HTR1AHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL5331285 | 0.93 | HTR2A (0.62) | HTR1AHTR2ADRD2DRD3DRD4 | |
| SCHEMBL5339214 | 0.91 | HTR1A (0.70) | HTR1AHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL5337334 | 0.89 | HTR2A (0.60) | HTR1AHTR2ADRD2DRD3DRD4 | |
| SCHEMBL5342960 | 0.86 | HTR1A (0.73) | HTR1AHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL5335868 | 0.86 | HTR1A (0.62) | HTR1AHTR2ADRD2 | |
| SCHEMBL5336902 | 0.84 | HTR1A (0.70) | HTR1AHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL5331709 | 0.83 | HTR2A (0.65) | HTR1AHTR2ADRD2DRD3DRD4 | |
| SCHEMBL5336185 | 0.83 | HTR1A (0.73) | HTR1AHTR2ADRD2DRD3SLC6A4 | |
| SCHEMBL5336128 | 0.83 | HTR1A (0.77) | HTR1AHTR2ADRD2DRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155795-A1 | MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS INC. (US) | 2007-07-05 | — | — | US | disclosed |
| US-7238713-B2 | Muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| EP-1535912-A1 | Muscarinic agonists | Arcadia Pharmaceuticals Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20050113357-A1 | Muscarinic agonists | ANDERSON CARL-MAGNUS A (DK) | 2005-05-26 | — | — | US | disclosed |
| US-6627645-B2 | Cholinergic agents | ACADIA PHARMACEUTICALS, INC. | 2003-09-30 | — | — | US | disclosed |
| US-20020037886-A1 | Muscarinic agonists | ACADIA PHARMACEUTICALS INC. | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037886-A1 | Muscarinic agonists | CHRM2, CHRM1, CHRM4 | HTR1A 118/4885HTR2A 235/4885DRD2 476/4885 |
| US-20070155795-A1 | MUSCARINIC AGONISTS | CHRM2, CHRM1, CHRM4 | HTR1A 118/4885HTR2A 235/4885DRD2 476/4885 |
| US-20050113357-A1 | Muscarinic agonists | CHRM2, CHRM1, CHRM4 | HTR1A 118/4885HTR2A 235/4885DRD2 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.