Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5319501 | 0.99 | KDM4E (0.37) | KDM4ENPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5318881 | 0.87 | DPP4 (0.48) | KDM4ENPC1RAB9ASMN1; SMN2AKT1 | |
| Hydrochloric Acid SCHEMBL5344135 | 0.86 | DPP4 (0.47) | KDM4ENPC1RAB9ASMN1; SMN2AKT1 | |
| SCHEMBL5337653 | 0.82 | DPP4 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2AKT1 | |
| SCHEMBL5321323 | 0.81 | AKT1 (0.50) | KDM4ENPC1RAB9ASMN1; SMN2AKT1 | |
| SCHEMBL5341559 | 0.79 | DPP4 (0.45) | NPC1TP53RAB9ASMN1; SMN2AKT1 | |
| SCHEMBL5344323 | 0.78 | CYP3A4 (0.44) | KDM4ERAB9ASMN1; SMN2AKT1AKT2 | |
| SCHEMBL5348641 | 0.78 | DPP4 (0.39) | KDM4ENPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5336486 | 0.77 | AKT1 (0.39) | KDM4ERAB9ASMN1; SMN2AKT1AKT2 | |
| SCHEMBL5320273 | 0.75 | DPP4 (0.52) | NPC1RAB9ASMN1; SMN2AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |