Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 7/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322366 | 0.88 | AKT1 (0.50) | CYP3A4CYP2C19SLC2A1AKT1AKT2 | |
| SCHEMBL5336486 | 0.84 | AKT1 (0.39) | CYP3A4CYP2C19CYP1A2DPP4DPP8 | |
| SCHEMBL5320273 | 0.82 | DPP4 (0.52) | CYP3A4CYP2C19CYP1A2SLC2A1DPP4 | |
| SCHEMBL5348641 | 0.81 | DPP4 (0.39) | CYP3A4CYP2C19CYP1A2DPP4DPP8 | |
| SCHEMBL5352678 | 0.81 | AKT1 (0.43) | CYP3A4CYP2C19CYP1A2LMNADPP4 | |
| SCHEMBL5336981 | 0.80 | MAPT (0.41) | CYP2C19CYP1A2LMNACYP2C9NPSR1 | |
| SCHEMBL5347503 | 0.80 | NR4A2 (0.46) | CYP3A4CYP2C19CYP1A2ROS1DPP4 | |
| SCHEMBL5335624 | 0.78 | KDM4E (0.38) | DPP4DPP8DPP9AKT1AKT2 | |
| SCHEMBL5341559 | 0.78 | DPP4 (0.45) | CYP3A4CYP2C19CYP1A2LMNACYP2C9 | |
| SCHEMBL5320900 | 0.78 | DPP4 (0.52) | CYP3A4CYP2C19CYP1A2SLC2A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |