Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800865 | 0.86 | MAPT (0.54) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3802381 | 0.86 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3792949 | 0.85 | MAPT (0.53) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3797304 | 0.84 | MAPT (0.50) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3803951 | 0.82 | MAPT (0.47) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3796350 | 0.82 | MAPT (0.41) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3793464 | 0.82 | MAPT (0.47) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14086931 | 0.80 | MAPT (0.54) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3803929 | 0.79 | MAPT (0.43) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3801076 | 0.79 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157473-B2 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection | RIGEL PHARMACEUTICALS, INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-20040127497-A1 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection | MIDCAP FINANCIAL TRUST | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127497-A1 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection | HAVCR2, HCCS, NQO1 | MAPT 4676/4885KMT2A 3703/4885MEN1 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.