Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.40 |
| ▸ | KDM5A | P29375 | 7/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820502 | 0.98 | KDM4C (0.39) | KDM4CKDM5AAPPLTA4HS1PR2 | |
| SCHEMBL12927451 | 0.94 | KDM4C (0.42) | KDM4CKDM5AAPPLTA4HS1PR2 | |
| SCHEMBL5263631 | 0.91 | S1PR2 (0.41) | KDM4CKDM5AAPPLTA4HS1PR2 | |
| SCHEMBL15870622 | 0.89 | S1PR2 (0.48) | KDM4CKDM5AAPPS1PR2S1PR1 | |
| SCHEMBL11553105 | 0.88 | S1PR2 (0.52) | KDM4CKDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL17453161 | 0.88 | S1PR2 (0.52) | KDM4CKDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL5339485 | 0.88 | S1PR2 (0.52) | KDM4CKDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL17817349 | 0.88 | S1PR2 (0.52) | KDM4CKDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL7246353 | 0.88 | S1PR2 (0.52) | KDM4CKDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL13155350 | 0.88 | S1PR2 (0.52) | KDM4CKDM5AS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107732002-B | Electroactive actuator, mechanical device comprising the same, and polymer electrolyte | 浦项工科大学校产学协力团 | 2020-09-18 | — | — | CN | disclosed |
| CN-107732002-A | Active actuators including its mechanical device and polymer dielectric | 浦项工科大学校产学协力团 | 2018-02-23 | — | — | CN | disclosed |
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |