SCHEMBL5336427

SCHEMBL5336427

CCCCCOC(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
ATM Q13315 2/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 3/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 3/20 0.46
ESR1 P03372 5/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
AKR1C4 P17516 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
NAAA Q02083 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5337511 0.98 MAPT (0.50) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL5331593 0.98 MAPT (0.50) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL7943728 0.98 MAPT (0.50) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL5335631 0.98 MAPT (0.50) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL5336507 0.95 ESR1 (0.50) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL5333456 0.93 TSHR (0.53) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL5334417 0.91 MAPT (0.55) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL7929658 0.91 MAPT (0.55) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL7918400 0.91 MAPT (0.55) MAPTL3MBTL1ATMLMNAGAA
SCHEMBL7929648 0.91 MAPT (0.55) MAPTL3MBTL1ATMLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7307041-B2 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2007-12-11 US disclosed
EP-1637338-B1 Substantially light-insensitive thermographic recording material AGFA GEVAERT (BE) 2007-04-04 EP disclosed
US-20060063670-A1 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA-GEVAERT (BE) 2006-03-23 US disclosed