SCHEMBL5336507

SCHEMBL5336507

CCCCOC(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.50
TSHR P16473 6/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 3/20 0.44
MAPK1 P28482 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2D6 P10635 1/20 0.44
NR1H2 P55055 1/20 0.44
RNASEL Q05823 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP3A4 P08684 3/20 0.42
CYP2C9 P11712 1/20 0.42
PDE4D Q08499 1/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
ATM Q13315 2/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5336427 0.95 MAPT (0.48) ESR1TSHRL3MBTL1TDP1LMNA
SCHEMBL5337511 0.93 MAPT (0.50) ESR1TSHRL3MBTL1LMNAMAPK1
SCHEMBL5331593 0.93 MAPT (0.50) ESR1TSHRL3MBTL1LMNAMAPK1
SCHEMBL5335631 0.93 MAPT (0.50) ESR1TSHRL3MBTL1LMNAMAPK1
SCHEMBL7943728 0.93 MAPT (0.50) ESR1TSHRL3MBTL1LMNAMAPK1
SCHEMBL5340890 0.93 ESR1 (0.56) ESR1TSHRL3MBTL1TDP1LMNA
SCHEMBL5333811 0.89 LMNA (0.46) ESR1TSHRL3MBTL1TDP1LMNA
SCHEMBL5333456 0.87 TSHR (0.53) ESR1TSHRL3MBTL1TDP1LMNA
SCHEMBL521819 0.87 ESR1 (0.58) ESR1TSHRL3MBTL1TDP1LMNA
SCHEMBL10896211 0.86 MAPT (0.55) ESR1TSHRL3MBTL1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7307041-B2 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2007-12-11 US disclosed
EP-1637338-B1 Substantially light-insensitive thermographic recording material AGFA GEVAERT (BE) 2007-04-04 EP disclosed
US-20060063670-A1 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA-GEVAERT (BE) 2006-03-23 US disclosed
EP-1637338-A1 Substantially light-insensitive thermographic recording material Agfa-Gevaert (BE) 2006-03-22 EP disclosed
EP-0249885-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-01-02 EP disclosed
US-4794101-A MIXTURE OF PHTHALIDE DYE, FLUORAN COMPOUND AND POLYVALENT METAL SALT OF AN AROMATIC CARBOXYLIC ACID KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-12-27 US disclosed
EP-0249885-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-12-23 EP disclosed