Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | ALPG | P10696 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096469 | 0.88 | ALDH1A1 (1.00) | ALDH1A1POLBTDP1LMNAKMT2A | |
| SCHEMBL6023593 | 0.85 | TDP1 (1.00) | ALDH1A1POLBTDP1LMNAHPGD | |
| SCHEMBL19281517 | 0.81 | GAA (0.71) | ALDH1A1POLBGAALMNAKMT2A | |
| SCHEMBL19299516 | 0.76 | KDM4E (1.00) | ALDH1A1GAALMNAKMT2AKDM4E | |
| SCHEMBL14096468 | 0.75 | ALDH1A1 (0.77) | ALDH1A1POLBTDP1LMNAKMT2A | |
| SCHEMBL5448009 | 0.75 | KMT2A (0.79) | ALDH1A1POLBGAALMNAKMT2A | |
| SCHEMBL4491643 | 0.75 | TDP1 (0.75) | ALDH1A1POLBTDP1LMNAHPGD | |
| SCHEMBL18905575 | 0.74 | TDP1 (0.74) | ALDH1A1POLBTDP1GAALMNA | |
| SCHEMBL11273843 | 0.73 | POLB (1.00) | ALDH1A1POLBGAALMNAKMT2A | |
| SCHEMBL11597341 | 0.73 | KMT2A (0.70) | ALDH1A1POLBGAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |