SCHEMBL5336692

SCHEMBL5336692

O=C(O)c1cc(F)c(F)c(F)c1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.44
NFE2L2 Q16236 1/20 0.44
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA4 P22748 2/20 0.41
CES2 O00748 4/20 0.40
CES1 P23141 4/20 0.40
KDM4E B2RXH2 2/20 0.39
ASPH Q12797 2/20 0.39
KDM8 Q8N371 2/20 0.39
ALB P02768 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
ACMSD Q8TDX5 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31041213 1.00 KEAP1 (0.44) KEAP1NFE2L2CA1CA2CA4
SCHEMBL30787973 0.90 CA1 (0.42) KEAP1NFE2L2CA1CA2CA4
SCHEMBL8846323 0.85 KEAP1 (0.40) KEAP1NFE2L2CA1CA2CA4
SCHEMBL28322551 0.84 CA1 (0.36) KEAP1NFE2L2CA1CA2CA4
SCHEMBL6114299 0.83 KDM4E (0.48) KEAP1NFE2L2CA1CA2CA4
SCHEMBL31488901 0.82 MAPT (0.42) CA1CA2KDM4EMEN1KMT2A
SCHEMBL5341471 0.82 CA1 (0.46) KEAP1NFE2L2CA1CA2CA4
SCHEMBL1713473 0.82 KEAP1 (0.44) KEAP1NFE2L2CA1CA2CA4
Fluoride SCHEMBL6445071 0.81 KEAP1 (0.47) KEAP1NFE2L2CA1CA2CA4
SCHEMBL503374 0.81 KEAP1 (0.47) KEAP1NFE2L2CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118183709-A Method for preparing fluorocarbon material by utilizing hydrothermal-carbonization method 重庆大学锂电及新材料遂宁研究院 2024-06-14 CN claimed
CN-106478968-A A kind of preparation method of nanometer of Kapton 陕西科技大学 2017-03-08 CN claimed
CN-103435440-A Synthesis method of 1,2,4-trifluoro benzene ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2013-12-11 CN claimed
CN-1038745-C Process for selective hydrodefluorination OCCIDENTAL CHEM CO (US) 1998-06-17 CN claimed
CN-1118344-A Processes for producing tetrafluorophthalic anhydride and fluorobenzoic acids ASAHI CO LTD (JP) 1996-03-13 CN claimed
CN-1077191-A PROCESS FOR SELECTIVE HYDRODEFLUORINATION OCCIDENTAL CHEM CO (US) 1993-10-13 CN claimed
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
CN-118183709-A Method for preparing fluorocarbon material by utilizing hydrothermal-carbonization method 重庆大学锂电及新材料遂宁研究院 2024-06-14 CN disclosed
CN-103435440-B Synthesis method of 1,2,4-trifluoro benzene ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2015-02-25 CN disclosed
CN-101681112-B Composition for forming antireflection film and method for forming resist pattern using the same TOKYO OHKA KOGYO CO LTD 2012-05-30 CN disclosed
CN-101681112-A Composition for forming antireflection film and method for forming resist pattern using the same TOKYO OHKA KOGYO CO LTD 2010-03-24 CN disclosed
CN-101652250-A Composite material ADEKA CORP JP 2010-02-17 CN disclosed
US-7217827-B2 Halogen-containing aromatic compound NIPPON SHOKUBAI CO., LTD. (JP) 2007-05-15 US disclosed
CN-1118344-A Processes for producing tetrafluorophthalic anhydride and fluorobenzoic acids ASAHI CO LTD (JP) 1996-03-13 CN disclosed
US-5294738-A Hydrolysis of imide and hydrodefluorination OCCIDENTAL CHEMICAL CORPORATION (US) 1994-03-15 US disclosed
EP-0569620-A1 Method of making 2,4,5-trihalobenzoic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1993-11-18 EP disclosed
CN-1077191-A PROCESS FOR SELECTIVE HYDRODEFLUORINATION OCCIDENTAL CHEM CO (US) 1993-10-13 CN disclosed
CN-1077191-A PROCESS FOR SELECTIVE HYDRODEFLUORINATION OCCIDENTAL CHEM CO (US) 1993-10-13 CN disclosed
EP-0563986-A2 Process for selective hydrodefluorination Occidental Chemical Corporation (US) 1993-10-06 EP disclosed
US-5196590-A Heating a trihalophthalimide compound, water, mineral acid OCCIDENTAL CHEMICAL CORPORATION (US) 1993-03-23 US disclosed