Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 11/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338888 | 0.84 | PRKCQ (0.50) | PRKCQPRKCDLRRK2CYP11B1CYP11B2 | |
| SCHEMBL7219741 | 0.77 | CYP11B1 (0.44) | PRKCQPRKCDLRRK2CYP11B1CYP11B2 | |
| SCHEMBL5329333 | 0.76 | ADORA2A (0.46) | PRKCQPRKCDLRRK2CYP11B1CYP11B2 | |
| SCHEMBL7220037 | 0.72 | ADORA1 (0.49) | CYP1A2CYP2C9CYP2C19NPSR1ADORA1 | |
| SCHEMBL169815 | 0.72 | CYP11B1 (0.49) | CYP11B1CYP11B2ALOX15CYP1A2CYP2C9 | |
| SCHEMBL2978375 | 0.72 | KDM5A (0.40) | PRKCQPRKCDLRRK2CYP11B1CYP11B2 | |
| SCHEMBL1146097 | 0.72 | CYP1A2 (0.57) | LRRK2CYP11B1CYP11B2CYP1A2CYP2C9 | |
| SCHEMBL7215513 | 0.72 | ATR (0.50) | LRRK2CYP11B1CYP11B2CYP1A2CYP2C9 | |
| SCHEMBL1922370 | 0.69 | PRKCQ (0.39) | PRKCQPRKCDCYP11B1CYP11B2 | |
| SCHEMBL1921036 | 0.69 | CYP11B1 (0.39) | PRKCQCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |