Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169815 | 0.88 | CYP11B1 (0.49) | CYP11B1CYP11B2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL3089783 | 0.81 | ADORA2A (0.47) | CYP11B1CYP11B2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL5329333 | 0.80 | ADORA2A (0.46) | CYP11B1CYP11B2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL5336784 | 0.77 | PRKCQ (0.54) | CYP11B1CYP11B2ADORA2AADORA1PRKCQ | |
| SCHEMBL7220037 | 0.76 | ADORA1 (0.49) | ADORA2AADORA1ALDH1A1KDM4EHTT | |
| SCHEMBL2978375 | 0.76 | KDM5A (0.40) | CYP11B1CYP11B2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL1146097 | 0.76 | CYP1A2 (0.57) | CYP11B1CYP11B2ALDH1A1KDM4EHTT | |
| SCHEMBL7215513 | 0.76 | ATR (0.50) | CYP11B1CYP11B2ALDH1A1KDM4EHTT | |
| SCHEMBL565466 | 0.75 | ESR2 (0.50) | ALDH1A1KDM4EMAPTHTTNPSR1 | |
| SCHEMBL28598885 | 0.73 | ATM (0.35) | ADORA2AADORA1KDRMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |