Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232602 | 0.86 | MAOA (0.71) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5238909 | 0.85 | MAOA (0.80) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5320223 | 0.85 | MAOA (0.80) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5324047 | 0.84 | MAOA (0.76) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5228881 | 0.84 | MAOA (0.76) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL4160608 | 0.84 | MAOA (0.78) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5234089 | 0.84 | MAOA (0.68) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5737970 | 0.83 | MAOA (0.74) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL24169742 | 0.83 | MAOA (1.00) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL18410322 | 0.83 | MAOA (1.00) | MAOAMAOBKCNH2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286998-B2 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | EP | disclosed |
| US-7141583-B2 | Oxazolidinone derivatives with antibiotic activity | ASTRAZENECA AB (SE) | 2006-11-28 | — | — | US | disclosed |
| EP-1286998-B1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2004-06-09 | — | — | EP | disclosed |