SCHEMBL5337461

SCHEMBL5337461

On1cc2ncncc2n1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28387105 0.76 EGFR (0.35) EGFR
SCHEMBL5052056 0.74 EGFR (0.34) EGFR
SCHEMBL23557654 0.69 HTT (0.32) EGFR
SCHEMBL3726363 0.69 EGFR (0.33) EGFR
SCHEMBL3843210 0.69 EGFR (0.31) EGFR
SCHEMBL127479 0.69 EGFR (0.50) EGFR
SCHEMBL309958 0.68 EGFR (0.33) EGFR
SCHEMBL28003243 0.67 EGFR (0.48) EGFR
SCHEMBL11821016 0.67
SCHEMBL6881642 0.65 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007069924-A1 DEAZAPURINE ANALOGS OF 4'-AZA-L-NUCLEOSIDES INDUSTRIAL RESEARCH LIMITED (NZ) 2007-06-21 WO disclosed
US-4345078-A Combating arthropods with O-alkyl-O-[5-carbalkoxy-7-alkyl-pyrazolo(1,5-α)-pyrimidin-2-yl]-(thiono) (thiol)-phosphoric (phosphonic) acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed
US-4067970-A NEMATOCIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-3950337-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed