Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.42 |
| ▸ | AKT2 | P31751 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342211 | 0.88 | SLC2A1 (0.47) | TSPOGMNNLMNAPOLBCYP3A4 | |
| SCHEMBL5318498 | 0.86 | AKT1 (0.48) | AKT1AKT2PTGS2TSPOGMNN | |
| SCHEMBL5489046 | 0.76 | AKT1 (0.46) | AKT1AKT2 | |
| SCHEMBL5338039 | 0.73 | AKT1 (0.45) | AKT1AKT2TSPOGMNNLMNA | |
| SCHEMBL5343284 | 0.72 | AKT1 (0.53) | AKT1AKT2PTGS2 | |
| SCHEMBL5341021 | 0.72 | AKT1 (0.49) | AKT1AKT2TSPOGMNNLMNA | |
| SCHEMBL5343498 | 0.71 | FYN (0.46) | AKT1AKT2PTGS2CYP3A4 | |
| SCHEMBL5322122 | 0.71 | CNR1 (0.41) | AKT1AKT2PTGS2MALT1CNR1 | |
| SCHEMBL5335061 | 0.71 | AKT1 (0.42) | AKT1AKT2PTGS2TSPOGMNN | |
| SCHEMBL5341752 | 0.70 | AKT1 (0.53) | AKT1AKT2TSPOGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |