Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.45 |
| ▸ | AKT2 | P31751 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CENPE | Q02224 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337099 | 0.82 | SMN1; SMN2 (0.44) | AKT1AKT2SMN1; SMN2TSPOGMNN | |
| SCHEMBL5341752 | 0.74 | AKT1 (0.53) | AKT1AKT2TSPOGMNNLMNA | |
| SCHEMBL5318498 | 0.73 | AKT1 (0.48) | AKT1AKT2TSPOGMNNLMNA | |
| SCHEMBL5337544 | 0.73 | AKT1 (0.42) | AKT1AKT2TSPOGMNNLMNA | |
| SCHEMBL5342248 | 0.72 | TSPO (0.47) | AKT1AKT2SMN1; SMN2TSPO | |
| SCHEMBL5357335 | 0.71 | KDM4E (0.48) | AKT1AKT2SMN1; SMN2TSPOGMNN | |
| SCHEMBL5344567 | 0.69 | SMN1; SMN2 (0.47) | AKT1AKT2SMN1; SMN2TSPOGMNN | |
| SCHEMBL5342211 | 0.67 | SLC2A1 (0.47) | SMN1; SMN2TSPOGMNNLMNAPOLB | |
| SCHEMBL5351210 | 0.66 | CNR1 (0.54) | AKT1AKT2 | |
| SCHEMBL5335702 | 0.66 | POLB (0.51) | AKT1AKT2TSPOGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |