Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133778 | 0.84 | MEN1 (0.48) | KMT2APOLBALDH1A1LMNAMAPT | |
| SCHEMBL5346421 | 0.83 | GAA (0.49) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL7925149 | 0.82 | GAA (0.54) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL11135278 | 0.80 | GAA (0.62) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL5619294 | 0.80 | GAA (0.43) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL5334067 | 0.79 | KDM4E (0.56) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL10947003 | 0.79 | GAA (0.45) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL29446988 | 0.78 | CA2 (0.62) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL18197 | 0.78 | CA2 (0.62) | GAAKMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL5317392 | 0.76 | GAA (0.50) | GAAKMT2APOLBALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| US-4371736-A | Herbicidal pyridinyloxy(pyrimidinyloxy)benzenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-01 | — | — | US | disclosed |
| EP-0061913-A2 | Herbicidal heterooxybenzenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-10-06 | — | — | EP | disclosed |