Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.72 |
| ▸ | ITGAV | P06756 | 5/20 | 0.72 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 8/20 | 0.49 |
| ▸ | CA2 | P00918 | 8/20 | 0.49 |
| ▸ | CA5A | P35218 | 8/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501722 | 1.00 | ITGB3 (0.72) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5338023 | 1.00 | ITGB3 (0.72) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5878680 | 0.87 | ITGB3 (0.84) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL27522238 | 0.86 | ITGB3 (0.66) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5878950 | 0.86 | ITGB3 (0.83) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5878954 | 0.86 | ITGB3 (0.83) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5878937 | 0.86 | ITGB3 (0.90) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5878648 | 0.85 | ITGB3 (0.81) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5878645 | 0.85 | ITGB3 (0.81) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL5878847 | 0.84 | ITGB3 (0.84) | ITGB3ITGAVF10MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220824-B1 | Integrin-mediated drug targeting | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| US-20060189544-A1 | Integrin-Mediated drug targeting | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189544-A1 | Integrin-Mediated drug targeting | ITGAV, ITGB3, ITGB1 | ITGB3 2/4885ITGAV 1/4885F10 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.