Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802558 | 0.83 | — | — | |
| SCHEMBL19409375 | 0.75 | THRB (0.64) | THRBTSHRALDH1A1GLO1LMNA | |
| SCHEMBL15030 | 0.75 | — | — | |
| Charcoal, Activated SCHEMBL7592908 | 0.73 | — | — | |
| Acetone SCHEMBL11325819 | 0.73 | THRB (0.61) | THRBTSHRALDH1A1GLO1LMNA | |
| Ammonia Solution, Strong SCHEMBL2598325 | 0.73 | — | — | |
| Ethane SCHEMBL21616541 | 0.73 | THRB (0.61) | THRBTSHRALDH1A1GLO1LMNA | |
| Hydrochloric Acid SCHEMBL675826 | 0.73 | — | — | |
| Ethylene SCHEMBL340677 | 0.73 | THRB (0.61) | THRBTSHRALDH1A1GLO1LMNA | |
| SCHEMBL11457945 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745012-A2 | COMPOSITIONS OF ALLOSTERIC HEMOGLOBIN MODIFIERS AND METHODS OF MAKING THE SAME | Allos Therapeutics, Inc. (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005102305-A2 | COMPOSITIONS OF ALLOSTERIC HEMOGLOBIN MODIFIERS AND METHODS OF MAKING THE SAME | ALLOS THERAPEUTICS, INC. (US) | 2005-11-03 | — | — | WO | disclosed |