Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.69 |
| ▸ | ITGAV | P06756 | 15/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835824 | 0.88 | ITGB3 (0.52) | ITGB3ITGAVMMP2MMP9ADAMTS4 | |
| SCHEMBL5338043 | 0.87 | ITGB3 (0.57) | ITGB3ITGAVMMP2MMP9ADAMTS4 | |
| SCHEMBL5338628 | 0.82 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL14501725 | 0.82 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5878473 | 0.76 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5336087 | 0.73 | ITGB3 (0.60) | ITGB3ITGAV | |
| SCHEMBL5339721 | 0.70 | ITGB3 (0.53) | ITGB3ITGAVADAMTS4 | |
| SCHEMBL5340108 | 0.69 | ITGB3 (0.59) | ITGB3ITGAV | |
| SCHEMBL3835821 | 0.68 | ITGB3 (0.79) | ITGB3ITGAVMMP2MMP9ADAMTS4 | |
| SCHEMBL14501729 | 0.68 | ITGB3 (0.79) | ITGB3ITGAVMMP2MMP9ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220824-B1 | Integrin-mediated drug targeting | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| US-20060189544-A1 | Integrin-Mediated drug targeting | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189544-A1 | Integrin-Mediated drug targeting | ITGAV, ITGB3, ITGB1 | ITGB3 2/4885ITGAV 1/4885CYP3A4 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.