Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533867 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2SLC22A1HTR1AADRA2ACHRM1 | |
| SCHEMBL2010954 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2SLC22A1HTR1AADRA2ACHRM1 | |
| SCHEMBL6824608 | 0.87 | TSHR (0.46) | SMN1; SMN2SLC22A1HTR1AADRA2ACHRM1 | |
| SCHEMBL6824604 | 0.87 | TSHR (0.46) | SMN1; SMN2SLC22A1HTR1AADRA2ACHRM1 | |
| SCHEMBL2164318 | 0.85 | CYP1A2 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29385007 | 0.85 | CYP1A2 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2164321 | 0.85 | CYP1A2 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL19900104 | 0.85 | NPSR1 (0.55) | SMN1; SMN2SLC22A1HTR1AADRA2ACHRM1 | |
| SCHEMBL21195765 | 0.85 | NPSR1 (0.55) | SMN1; SMN2SLC22A1HTR1AADRA2ACHRM1 | |
| SCHEMBL5302952 | 0.85 | CYP1A2 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118511884-A | Application of 2, 6-dichlorobenzaldehyde oxime in inhibiting weed growth | 兰州石化职业技术大学 | 2024-08-20 | — | — | CN | claimed |
| CN-114950279-A | Reaction kettle for preparing 2, 6-difluorobenzonitrile and production process | 江西国化实业有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-109174200-A | A kind of catalyst, preparation method and synthetic method synthesizing 1,1- diethoxyethane | 中国科学院成都有机化学有限公司 | 2019-01-11 | — | — | CN | claimed |
| US-4443247-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1984-04-17 | — | — | US | claimed |
| US-12486259-B2 | FXR agonist having pyrazine structure, and preparation method and use | JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) | 2025-12-02 | — | — | US | disclosed |
| US-20250115608-A1 | HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS | ARDELYX, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-12209088-B2 | Hormone receptor modulators for treating metabolic conditions and disorders | ARDELYX, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| CN-114656460-B | Novel pyrazine FXR agonist, preparation method and application | 江苏天士力帝益药业有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-117797770-B | Stationary phase supported molecular sieve for separating mixed dichlorotoluene, preparation and use method thereof | 江苏丰山生化科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115504972-B | Isoxazole derivatives, preparation method thereof and application thereof as medicines | 广东药科大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-113582807-B | Method for synthesizing 2, 6-dichloro dichlorobenzyl | 江苏聚由新材料科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-118511884-A | Application of 2, 6-dichlorobenzaldehyde oxime in inhibiting weed growth | 兰州石化职业技术大学 | 2024-08-20 | — | — | CN | disclosed |
| EP-0077854-A1 | Herbicidal halogenated aromatic aminooxyacetic acid compounds and methods of use | UNION CARBIDE CORPORATION (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4380661-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1983-04-19 | — | — | US | disclosed |
| EP-0002246-B1 | OXIME ESTERS, HERBICIDES CONTAINING THEM, THEIR USE AS HERBICIDES AS WELL AS A PROCESS FOR THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-01-20 | — | — | EP | disclosed |
| US-4283403-A | Substituted isoxazolines for control of plant phytopathogens | ELI LILLY AND COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| US-4200587-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1980-04-29 | — | — | US | disclosed |
| EP-0002246-A2 | Oxime esters, herbicides containing them, their use as herbicides as well as a process for their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-06-13 | — | — | EP | disclosed |
| US-3941839-A | HERBICIDE | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | disclosed |
| US-3941832-A | Oxime ethers and pesticidal preparations containing them | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12209088-B2 | Hormone receptor modulators for treating metabolic conditions and disorders | NR1H4, FXR1, GLP1R | SMN1; SMN2 4807/4885SLC22A1 426/4885HTR1A 836/4885 |
| US-12486259-B2 | FXR agonist having pyrazine structure, and preparation method and use | FXR1, NR1H4, SLC10A1 | SMN1; SMN2 4803/4885SLC22A1 493/4885HTR1A 2115/4885 |
| US-20250115608-A1 | HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS | NR1H4, FXR1, GLP1R | SMN1; SMN2 4807/4885SLC22A1 426/4885HTR1A 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.