SCHEMBL533939

SCHEMBL533939

Nc1cc(O)ccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31065953 1.00
Carbon Dioxide SCHEMBL28257141 0.84 CA12 (0.39)
Tetrahydrofuran SCHEMBL28791245 0.84 CA12 (0.39)
SCHEMBL33965 0.79
Hydrochloric Acid SCHEMBL2291784 0.77 ALDH1A1 (0.54)
SCHEMBL5514128 0.75 ESR1 (0.48)
SCHEMBL29458034 0.75
SCHEMBL15677 0.75
SCHEMBL29617579 0.75
SCHEMBL543834 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393642-B Preparation method of fluorine-containing autocatalytic phthalonitrile resin 河北工业大学 2022-07-26 CN claimed
CN-111393642-A Preparation method of fluorine-containing autocatalytic phthalonitrile resin 河北工业大学 2020-07-10 CN claimed
CN-106748830-B A kind of preparation method of 3- amino-4-fluorophenol 金凯(辽宁)化工有限公司 2018-11-30 CN claimed
CN-106748830-A A kind of preparation method of the fluorophenol of 3 amino 4 金凯(辽宁)化工有限公司 2017-05-31 CN claimed
CN-102432592-A Aryl urea derivative with anti-tumor effect and preparation method thereof UNIV PEKING FOUNDER GROUP CO 2012-05-02 CN claimed
CN-101450906-B Method for preparing 3-amino-4-fluorophenol TAIXING CHEMSPEC CHEMICALS CO LTD 2011-06-22 CN claimed
CN-101519357-A Method for preparing 3-amino-4-fluorophenol BINHAI KANGJIE CHEMISTRY CO LT 2009-09-02 CN claimed
CN-101450906-A Method for preparing 3-amino-4-fluorophenol TAIXING KANGPENG CHEMICALS CO (CN) 2009-06-10 CN claimed
US-4563535-A Process for producing tetrahydrophthalimides SUMITOMO CHEMICAL CO., LTD. (JP) 1986-01-07 US claimed
EP-0150064-A2 3-Amino-4-fluorophenylethers and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-31 EP claimed
EP-0141972-A1 Process for producing tetrahydrophthalimides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-22 EP claimed
JP-60064961-A None JP disclosed
JP-60067449-A None JP disclosed
JP-60152449-A None JP disclosed
JP-60158147-A None JP disclosed
EP-0141972-A1 Process for producing tetrahydrophthalimides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-22 EP disclosed
JP-S6067449-A PRODUCTION OF 3-AMINO-4-FLUOROPHENOL SUMITOMO CHEM CO LTD 1985-04-17 JP disclosed
JP-S6064961-A PHTHALIMIDE DERIVATIVE AND PRODUCTION THEREOF SUMITOMO CHEM CO LTD 1985-04-13 JP disclosed
JP-S5883659-A 3-AMINO-4-FLUOROPHENOL DERIVATIVE AND ITS PREPARATION SUMITOMO CHEM CO LTD 1983-05-19 JP disclosed
US-4006185-A CHEMICAL INTERMEDIATES OLIN CORPORATION (US) 1977-02-01 US disclosed