⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278494 | 0.67 | HSD17B10 (0.31) | — | |
| SCHEMBL5011876 | 0.65 | — | — | |
| SCHEMBL3125602 | 0.65 | — | — | |
| SCHEMBL7458711 | 0.65 | — | — | |
| SCHEMBL533260 | 0.65 | — | — | |
| SCHEMBL2752735 | 0.63 | F2RL3 (0.33) | — | |
| SCHEMBL533888 | 0.61 | — | — | |
| SCHEMBL314388 | 0.60 | — | — | |
| SCHEMBL314017 | 0.60 | — | — | |
| SCHEMBL972636 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655592-A | Preparation method of intermediate of fluorothiazole pyrithione | 顺毅南通化工有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-108373476-A | A kind of kinase inhibitor and its preparation and application | 成都地奥制药集团有限公司 | 2018-08-07 | — | — | CN | claimed |
| CN-103570614-B | The hydrazide derivatives of pyridine 2 and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-12-01 | — | — | CN | claimed |
| WO-2017064156-A1 | NOVEL 6-FUSED AND 2-HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2017-04-20 | — | — | WO | claimed |
| CN-103570614-A | Pyridine-2-hydrazide derivatives, preparation method, drug compositions and uses thereof | INST MATERIA MEDICA CAMS | 2014-02-12 | — | — | CN | claimed |
| EP-1765816-B1 | SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS | GRUENENTHAL GMBH (DE) | 2010-03-10 | — | — | EP | claimed |
| US-7300939-B2 | Substituted 1-propiolylpiperazine compounds, their preparation and use | GRUENENTHAL GMBH (DE) | 2007-11-27 | — | — | US | claimed |
| US-20070112011-A1 | Substituted 1-propiolylpiperazine compounds, their preparation and use | GRUENENTHAL GMBH (DE) | 2007-05-17 | — | — | US | claimed |
| EP-1765816-A1 | SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS | Grünenthal GmbH (DE) | 2007-03-28 | — | — | EP | claimed |
| WO-2006002981-A1 | SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS | Grünenthal GmbH (DE) | 2006-01-12 | — | — | WO | claimed |
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | claimed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | claimed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | claimed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | claimed |
| CN-118308243-A | Siamese bacillus and fluorothiazole pyrithione compound composition and application thereof | 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) | 2024-07-09 | — | — | CN | disclosed |
| EP-4382546-A1 | POLY(UREA-URETHANE) POLYMER | BASF SE (DE) | 2024-06-12 | — | — | EP | disclosed |
| WO-2006002981-A1 | SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS | Grünenthal GmbH (DE) | 2006-01-12 | — | — | WO | disclosed |
| EP-1600442-A1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-1598349-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |