SCHEMBL533260

SCHEMBL533260

Clc1cs[c]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8426769 0.73
SCHEMBL2750938 0.69 KMO (0.33)
SCHEMBL17626166 0.68 AHR (0.35)
SCHEMBL3241324 0.65 TTR (0.46)
SCHEMBL971569 0.65
SCHEMBL125326 0.65
SCHEMBL3125602 0.65
SCHEMBL533958 0.65
SCHEMBL7458711 0.65
SCHEMBL5011876 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390259-A1 PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-12-07 US claimed
CN-116969964-A 5-azacyclo-structure-substituted macleaya cordata sanguinarine derivative with antibacterial and insecticidal activities and preparation method and application thereof 铜仁职业技术学院 2023-10-31 CN claimed
CN-112457322-B Insecticidal and antibacterial 5-imino substituted derivative, and preparation method and application thereof 铜仁职业技术学院 2022-06-17 CN claimed
CN-114573561-A Benzyl or heterocyclic substituted triazinone compound and preparation method and application thereof 中国农业大学 2022-06-03 CN claimed
US-20210085658-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PYRIDONE DERIVATIVES SK BIOPHARMACEUTICALS CO., LTD. 2021-03-25 US claimed
CN-112457322-A Insecticidal and antibacterial 5-imino substituted derivative and preparation method and application thereof 铜仁职业技术学院 2021-03-09 CN claimed
CN-112079846-A Sanguinarine derivative and chelerythrine derivative and application thereof 贵州梵净山生态农业股份有限公司 2020-12-15 CN claimed
US-10456385-B2 Pharmaceutical composition comprising pyridone derivatives SK BIOPHARMACEUTICALS CO., LTD. (KR) 2019-10-29 US claimed
US-20180263965-A1 PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES SK BIOPHARMACEUTICALS CO LTD (KR) 2018-09-20 US claimed
US-9987259-B2 Pharmaceutical composition comprising pyridone derivatives SK BIOPHARMACEUTICALS CO., LTD. (KR) 2018-06-05 US claimed
EP-1286988-A2 1-(H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL DERIVATIVES Basilea Pharmaceutica AG (CH) 2003-03-05 EP claimed
EP-0540143-B1 Compounds and methods for inhibition of HIV and related viruses MEDIVIR AB (SE) 2003-02-05 EP claimed
US-20010047017-A1 Azole derivatives HOFFMANN-LA ROCHE, INC. 2001-11-29 US claimed
US-6319933-B1 1-(1H-1,2,4-triazol-1-yl)butan-2-ol derivatives; fungicides BASILEA PHARMACEUTICA AG (CH) 2001-11-20 US claimed
WO-2001079196-A2 1-(H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL DERIVATIVES BASILEA PHARMACEUTICA AG (CH) 2001-10-25 WO claimed
US-6252072-B1 HYDROLYSIS OF THE CORRESPONDING TRIAZINE COMPOUND SYNGENTA CROP PROTECTION, INC. 2001-06-26 US claimed
US-5658907-A THIOUREA VIRICIDES MEDIVIR A/B (SE) 1997-08-19 US claimed
EP-0540143-A2 Compounds and methods for inhibition of HIV and related viruses Medivir Aktiebolag (SE) 1993-05-05 EP claimed
WO-1993003022-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1993-02-18 WO claimed
US-4259336-A ANALGESIC, ANTIPYRETIC, ANTITHROMBOTIC, ANTIPHLOGISTIC BOEHRINGER INGELHEIM GMBH (DE) 1981-03-31 US claimed