Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 10/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533907 | 0.88 | PTGS2 (0.38) | PTGS2PTGS1CHRM4GHSRPTGDR2 | |
| SCHEMBL534931 | 0.83 | CHRM4 (0.38) | PTGS2PTGS1CHRM4GHSRPTGDR2 | |
| SCHEMBL534013 | 0.81 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL534018 | 0.80 | PTGDR2 (0.44) | CHRM4GHSRPTGDR2 | |
| SCHEMBL534036 | 0.73 | CHRM4 (0.38) | PTGS2PTGS1CHRM4PTGDR2 | |
| SCHEMBL534040 | 0.72 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL3773874 | 0.70 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL534794 | 0.69 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL3779349 | 0.69 | PTGDR2 (0.59) | PTGS2GHSRPTGDR2 | |
| SCHEMBL534778 | 0.68 | PTGDR2 (0.48) | CHRM4PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129661-B1 | QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-02-08 | — | — | EP | claimed |